病理证实一个25岁的前大学足球运动员患有慢性创伤性脑病
Pathologically Confirmed Chronic Traumatic Encephalopathy in a 25-Year-Old Former College Football Player JesseMez,MD, MS1,2; Todd M.Solomon,PhD1; Daniel H.Daneshvar,MA1,3; Thor D.Stein,MD, PhD1,4,5,
Pathologically Confirmed Chronic Traumatic Encephalopathy in a 25-Year-Old Former College Football Player
Jesse Mez, MD, MS1,2; Todd M. Solomon, PhD1; Daniel H. Daneshvar, MA1,3; Thor D. Stein, MD, PhD1,4,5,6; Ann C. McKee, MD1,2,4,5,6
Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with repetitive head impacts.1 Presently, CTE only can be diagnosed pathologically; however, research efforts, such as the ongoing Understanding Neurological Injury and Traumatic Encephalopathy (UNITE) Study,2 are investigating ways to diagnose CTE during life. As part of the UNITE Study, a panel of clinicians, blinded to neuropathology, make retrospective clinical consensus diagnoses using published criteria, including proposed clinical research criteria for CTE.3 Here, we present an informative case from the UNITE Study.
JAMA Neurol. 2016;73(3):353-355. doi:10.1001/jamaneurol.2015.3998.
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